Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study

A history of childhood adversity is associated with psychotic disorder, with an increase in risk according to number or severity of exposures. However, it is not known why only some exposed individuals go on to develop psychosis. One possibility is pre-existing genetic vulnerability. Research on gen...

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Veröffentlicht in:PLoS One
Hauptverfasser: Trotta, Antonella, Iyegbe, Conrad, Di Forti, Marta, Sham, Pak C., Campbell, Desmond D., Cherny, Stacey S., Mondelli, Valeria, Aitchison, Katherine J., Murray, Robin M., Vassos, Evangelos, Fisher, Helen L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029892/
https://ncbi.nlm.nih.gov/pubmed/27648571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163319
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