Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders

BACKGROUND: There is increasing evidence for shared genetic susceptibility between schizophrenia and bipolar disorder. Although genetic variants only convey subtle increases in risk individually, their combination into a polygenic risk score constitutes a strong disease predictor. AIMS: To investiga...

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Publicat a:Br J Psychiatry
Autors principals: Calafato, Maria Stella, Thygesen, Johan H., Ranlund, Siri, Zartaloudi, Eirini, Cahn, Wiepke, Crespo-Facorro, Benedicto, Díez-Revuelta, Álvaro, Di Forti, Marta, Hall, Mei-Hua, Iyegbe, Conrad, Jablensky, Assen, Kahn, Rene, Kalaydjieva, Luba, Kravariti, Eugenia, Lin, Kuang, McDonald, Colm, McIntosh, Andrew M., McQuillin, Andrew, Picchioni, Marco, Rujescu, Dan, Shaikh, Madiha, Toulopoulou, Timothea, Os, Jim Van, Vassos, Evangelos, Walshe, Muriel, Powell, John, Lewis, Cathryn M., Murray, Robin M., Bramon, Elvira
Format: Artigo
Idioma:Inglês
Publicat: Cambridge University Press 2018
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Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130805/
https://ncbi.nlm.nih.gov/pubmed/30113282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1192/bjp.2018.89
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