A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

This large multi‐center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi‐modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients with psychosis, 822 unaffected first‐degree relatives of patients, and 2,333 c...

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Detalhes bibliográficos
Publicado no:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Ranlund, Siri, Calafato, Stella, Thygesen, Johan H., Lin, Kuang, Cahn, Wiepke, Crespo‐Facorro, Benedicto, de Zwarte, Sonja M.C., Díez, Álvaro, Di Forti, Marta, Iyegbe, Conrad, Jablensky, Assen, Jones, Rebecca, Hall, Mei‐Hua, Kahn, Rene, Kalaydjieva, Luba, Kravariti, Eugenia, McDonald, Colm, McIntosh, Andrew M., McQuillin, Andrew, Picchioni, Marco, Prata, Diana P., Rujescu, Dan, Schulze, Katja, Shaikh, Madiha, Toulopoulou, Timothea, van Haren, Neeltje, van Os, Jim, Vassos, Evangelos, Walshe, Muriel, Lewis, Cathryn, Murray, Robin M., Powell, John, Bramon, Elvira
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763362/
https://ncbi.nlm.nih.gov/pubmed/28851104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32581
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