A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

This large multi‐center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi‐modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients with psychosis, 822 unaffected first‐degree relatives of patients, and 2,333 c...

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Bibliografiske detaljer
Udgivet i:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Ranlund, Siri, Calafato, Stella, Thygesen, Johan H., Lin, Kuang, Cahn, Wiepke, Crespo‐Facorro, Benedicto, de Zwarte, Sonja M.C., Díez, Álvaro, Di Forti, Marta, Iyegbe, Conrad, Jablensky, Assen, Jones, Rebecca, Hall, Mei‐Hua, Kahn, Rene, Kalaydjieva, Luba, Kravariti, Eugenia, McDonald, Colm, McIntosh, Andrew M., McQuillin, Andrew, Picchioni, Marco, Prata, Diana P., Rujescu, Dan, Schulze, Katja, Shaikh, Madiha, Toulopoulou, Timothea, van Haren, Neeltje, van Os, Jim, Vassos, Evangelos, Walshe, Muriel, Lewis, Cathryn, Murray, Robin M., Powell, John, Bramon, Elvira
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763362/
https://ncbi.nlm.nih.gov/pubmed/28851104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32581
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