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59.2 Matrix Metalloproteinase Inhibition Prevents the Adult Excitatory-Inhibitory Imbalance Induced by the Reciprocal Interaction Between Neuroinflammation and Oxidative Stress During Development

Background: Besides oxidative stress, evidence indicates the implication of immune dysregulation in schizophrenia. As oxidative stress is known to induce inflammation, we explored the mechanisms involved in their interaction using an animal model of redox dysregulation, the GCLM KO mouse, in which a...

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Détails bibliographiques
Publié dans:Schizophr Bull
Auteurs principaux: Dwir, Daniella, Cabungcal, Jan-Harry, Tenenbaum, Liliane, Steullet, Pascal, Cuenod, Michel, Do, Kim
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475541/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.084
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