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SA102. N-Acetyl-Cysteine Treatment and Environmental Enrichment Reversed the Long-Lasting Effect of Oxidative Stress on PVI Circuitry: Relevance for Schizophrenia

Background: A hallmark of the pathophysiology of schizophrenia is a dysfunction of parvalbumin-expressing fast-spiking interneurons (PVI), which are essential for neuronal synchrony during sensory and cognitive processing. Oxidative stress and inflammation, as observed in schizophrenia, affects the...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Dwir, Daniella, Cabungcal, Jan-Harry, Steullet, Pascal, Schnider, Mirko, Cuénod, Michel, Do, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475993/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx023.100
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