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59.2 Matrix Metalloproteinase Inhibition Prevents the Adult Excitatory-Inhibitory Imbalance Induced by the Reciprocal Interaction Between Neuroinflammation and Oxidative Stress During Development

Background: Besides oxidative stress, evidence indicates the implication of immune dysregulation in schizophrenia. As oxidative stress is known to induce inflammation, we explored the mechanisms involved in their interaction using an animal model of redox dysregulation, the GCLM KO mouse, in which a...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Dwir, Daniella, Cabungcal, Jan-Harry, Tenenbaum, Liliane, Steullet, Pascal, Cuenod, Michel, Do, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475541/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.084
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