TRTH-19. PRECLINICAL ANALYSIS OF SODIUM VALPROATE FOR THE TREATMENT OF DIPG BY CONVECTION ENHANCED DELIVERY

There is a significant need to develop new treatment strategies to improve the prognosis of DIPG patients. We have previously shown that the HDAC inhibitor, sodium valproate (VPA), reduces the viability of DIPG cells in vitro. Whilst, VPA does cross the blood brain barrier, only 15% of serum concent...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Killick-Cole, Clare, Bienemann, Ali, Asby, Daniel, Singleton, William, Wyatt, Marcella, Boulter, Lisa, Barua, Neil, Gill, Steven
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475205/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.230
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars