TMOD-04. A UNIQUE PEDIATRIC IDH1 MUTANT GLIOBLASTOMA IN VITRO AND IN VIVO MODEL

The isocitrate dehydrogenase 1 (IDH1) mutation serves as a hallmark for secondary high-grade gliomas, occurring in approximately 80% of all secondary glioblastomas (GBM) in adults. IDH1 mutations in pediatric high-grade gliomas are much rarer, and its role is still largely unknown. The lack of biolo...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Metselaar, Dennis S., Meel, Michaël H., Waranecki, Piotr, Zwaan, Kenn, Poddighe, Pino J., van Vuurden, Dannis G., Kaspers, Gertjan L., Hulleman, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475176/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.203
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