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MEDU-50. TRANSCRIPTIONAL REGULATION OF THE HOMEOBOX GENES CRX AND OTX2 - IMPLICATIONS FOR MEDULLOBLASTOMA GROUP 3
BACKGROUND: Generation of disease-specific models and development of new treatments for non-WNT/non-SHH medulloblastomas (MB) is an urgent need. Group 3 MB is characterized by amplifications of MYC and/or OTX2. Furthermore, transcriptional profiling of group 3 MB shows dysregulation of GABAergic and...
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| Publicado en: | Neuro Oncol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475170/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.199 |
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