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MEDU-35. AN EPIGENOME FOCUSED RNAI SCREEN REVEALS SETD8 AS A KEY REGULATOR OF MYC DRIVEN MEDULLOBLASTOMA

The accumulating evidence of epigenetic deregulation during Medulloblastoma (MB) tumorigenesis provides an opportunity to identify novel directed therapeutics to improve patient outcome. However which epigenetic regulators are functionally critical for Myc-driven medulloblastoma is unclear. To addre...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Veo, Bethany, Venkataraman, Sujatha, Pierce, Angela, Foreman, Nicholas, Vibhakar, Rajeev
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475159/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.185
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