MEDU-35. AN EPIGENOME FOCUSED RNAI SCREEN REVEALS SETD8 AS A KEY REGULATOR OF MYC DRIVEN MEDULLOBLASTOMA

The accumulating evidence of epigenetic deregulation during Medulloblastoma (MB) tumorigenesis provides an opportunity to identify novel directed therapeutics to improve patient outcome. However which epigenetic regulators are functionally critical for Myc-driven medulloblastoma is unclear. To addre...

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Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Veo, Bethany, Venkataraman, Sujatha, Pierce, Angela, Foreman, Nicholas, Vibhakar, Rajeev
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
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Abstracts
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475159/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.185
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