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HGG-21. IDENTIFICATION OF SMALL MOLECULE KINASE INHIBITORS WITH SPECIFIC ACTIVITY IN PEDIATRIC GLIOMA
HYPOTHESIS: We hypothesize that pediatric high-grade glioma (pedHGG) tumors are sustained by pro-survival and pro-growth kinase signaling pathways that are distinct from adult GBM and normal brain, and can thereby be specifically targeted with small molecule inhibitors. METHODS: We performed a high-...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475075/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.110 |
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