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HGG-21. IDENTIFICATION OF SMALL MOLECULE KINASE INHIBITORS WITH SPECIFIC ACTIVITY IN PEDIATRIC GLIOMA

HYPOTHESIS: We hypothesize that pediatric high-grade glioma (pedHGG) tumors are sustained by pro-survival and pro-growth kinase signaling pathways that are distinct from adult GBM and normal brain, and can thereby be specifically targeted with small molecule inhibitors. METHODS: We performed a high-...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Simonds, Erin, Aghaeepour, Nima, Cayanan, Geraldine, Park, Joshua, Nolan, Garry, Weiss, William
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475075/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.110
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