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STEM-22. Single-cell mass cytometry of human glioblastoma reveals phenotypic heterogeneity and distinct cell cycle and epigenetic states among glioma stem cells

RATIONALE: Human glioblastoma (GBM) tumors harbor a subpopulation of glioma stem cells (GSCs) with the unique capacity to re-establish tumors as xenografts. While GSCs were recently shown to be the predominant cycling population in oligodendroglioma (Tirosh et al. Nature 2016), this relationship has...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Simonds, Erin, Cayanan, Geraldine, Park, Joshua, Bendall, Sean, Nolan, Garry, Weiss, William
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692431/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.937
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