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Engineered Exosomes as Vehicles for Biologically Active Proteins

Exosomes represent an attractive vehicle for the delivery of biomolecules. However, mechanisms for loading functional molecules into exosomes are relatively unexplored. Here we report the use of the evolutionarily conserved late-domain (L-domain) pathway as a mechanism for loading exogenous proteins...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Sterzenbach, Ulrich, Putz, Ulrich, Low, Ley-Hian, Silke, John, Tan, Seong-Seng, Howitt, Jason
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474961/
https://ncbi.nlm.nih.gov/pubmed/28412169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.03.030
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