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Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons

The regulation of metal ion transport within neurons is critical for normal brain function. Of particular importance is the regulation of redox metals such as iron (Fe), where excess levels can contribute to oxidative stress and protein aggregation, leading to neuronal death. The divalent metal tran...

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Detalhes bibliográficos
Main Authors: Howitt, Jason, Putz, Ulrich, Lackovic, Jenny, Doan, Anh, Dorstyn, Loretta, Cheng, Hong, Yang, Baoli, Chan-Ling, Tailoi, Silke, John, Kumar, Sharad, Tan, Seong-Seng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741278/
https://ncbi.nlm.nih.gov/pubmed/19706893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904880106
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