Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons

The regulation of metal ion transport within neurons is critical for normal brain function. Of particular importance is the regulation of redox metals such as iron (Fe), where excess levels can contribute to oxidative stress and protein aggregation, leading to neuronal death. The divalent metal tran...

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Bibliografiske detaljer
Main Authors: Howitt, Jason, Putz, Ulrich, Lackovic, Jenny, Doan, Anh, Dorstyn, Loretta, Cheng, Hong, Yang, Baoli, Chan-Ling, Tailoi, Silke, John, Kumar, Sharad, Tan, Seong-Seng
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741278/
https://ncbi.nlm.nih.gov/pubmed/19706893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904880106
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