ISOFORM SPECIFIC REGULATION OF DIVALENT METAL (ION) TRANSPORTER (DMT1) BY PROTEASOMAL DEGRADATION

DMT1 is the major transporter for iron entrance into mammalian cells and iron exit from endosomes during the transferrin cycle. Four major mRNA isoforms correspond to 4 protein isoforms, differing at 5'/3' and N-/C- termini, respectively. Isoforms are designated 1A vs. 1B reflecting where...

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Hoofdauteurs: Garrick, Michael D., Zhao, Lin, Roth, Jerome A., Jiang, Houbo, Feng, Jian, Foot, Natalie J., Dalton, Hazel, Kumar, Sharad, Garrick, Laura M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493171/
https://ncbi.nlm.nih.gov/pubmed/22310887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10534-012-9522-1
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