Cellular Up-regulation of Nedd4 Family Interacting Protein 1 (Ndfip1) using Low Levels of Bioactive Cobalt Complexes

The delivery of metal ions using cell membrane-permeable metal complexes represents a method for activating cellular pathways. Here, we report the synthesis and characterization of new [Co(III)(salen)(acac)] complexes capable of up-regulating the ubiquitin ligase adaptor protein Ndfip1. Ndfip1 is a...

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Bibliographic Details
Main Authors: Schieber, Christine, Howitt, Jason, Putz, Ulrich, White, Jonathan M., Parish, Clare L., Donnelly, Paul S., Tan, Seong-Seng
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048738/
https://ncbi.nlm.nih.gov/pubmed/21187286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203448
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