Nedd4 Family Interacting Protein 1 (Ndfip1) Is Required for Ubiquitination and Nuclear Trafficking of BRCA1-associated ATM Activator 1 (BRAT1) during the DNA Damage Response

During injury, cells are vulnerable to apoptosis from a variety of stress conditions including DNA damage causing double-stranded breaks. Without repair, these breaks lead to aberrations in DNA replication and transcription, leading to apoptosis. A major response to DNA damage is provided by the pro...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Low, Ley-Hian, Chow, Yuh-Lit, Li, Yijia, Goh, Choo-Peng, Putz, Ulrich, Silke, John, Ouchi, Toru, Howitt, Jason, Tan, Seong-Seng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358134/
https://ncbi.nlm.nih.gov/pubmed/25631046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.613687
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