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Ketamine induces motor neuron toxicity and alters neurogenic and proneural gene expression in zebrafish

Ketamine, a noncompetitive antagonist of N-methyl-D-aspartate-type glutamate receptors, is a pediatric anesthetic that has been shown to be neurotoxic in rodents and nonhuman primates when administered during the brain growth spurt. Recently, the zebrafish has become an attractive model for toxicity...

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Detalhes bibliográficos
Publicado no:J Appl Toxicol
Main Authors: Kanungo, Jyotshna, Cuevas, Elvis, Ali, Syed F., Paule, Merle G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474752/
https://ncbi.nlm.nih.gov/pubmed/22045596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.1751
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