Distinct effects of ketamine and acetyl l-carnitine on the dopamine system in zebrafish

Ketamine, a noncompetitive N-methyl-d-aspartic acid (NMDA) receptor antagonist is commonly used as a pediatric anesthetic. We have previously shown that acetyl L-carnitine (ALCAR) prevents ketamine toxicity in zebrafish embryos. In mammals, ketamine is known to modulate the dopaminergic system. NMDA...

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Vydáno v:Neurotoxicol Teratol
Hlavní autoři: Robinson, Bonnie L., Dumas, Melanie, Cuevas, Elvis, Gu, Qiang, Paule, Merle G., Ali, Syed F., Kanungo, Jyotshna
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924529/
https://ncbi.nlm.nih.gov/pubmed/26898327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ntt.2016.02.004
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