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Mechanistic studies on ketamine-induced mitochondrial toxicity in zebrafish embryos

Ketamine, a phencyclidine derivative, is an antagonist of the Ca(2+)-permeable N-methyl-D-aspartate (NMDA)-type glutamate receptors. It is a pediatric anesthetic and has been implicated in developmental neurotoxicity. Ketamine has also been shown to deplete ATP in mammalian cells. Our previous studi...

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Bibliografiske detaljer
Udgivet i:Neurotoxicol Teratol
Main Authors: Robinson, Bonnie L., Dumas, Melanie, Ali, Syed F., Paule, Merle G., Gu, Qiang, Kanungo, Jyotshna
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992061/
https://ncbi.nlm.nih.gov/pubmed/29225006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ntt.2017.12.005
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