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Ketamine attenuates cytochrome p450 aromatase gene expression and estradiol-17β levels in zebrafish early life stages

Ketamine, a dissociative anesthetic, is a noncompetitive antagonist of N-methyl-D-aspartate-type glutamate receptors. In rodents and non-human primates as well as in zebrafish embryos, ketamine has been shown to be neurotoxic. In cyclic female rats, ketamine has been shown to decrease serum estradio...

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Detalles Bibliográficos
Publicado en:J Appl Toxicol
Main Authors: Trickler, William J., Guo, Xiaoqing, Cuevas, Elvis, Ali, Syed F., Paule, Merle G., Kanungo, Jyotshna
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474754/
https://ncbi.nlm.nih.gov/pubmed/23696345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.2888
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