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Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay

The spindle assembly checkpoint (SAC) delays mitotic progression until all sister chromatid pairs achieve bi-orientation, and while the SAC can maintain mitotic arrest for extended periods, moderate delays in mitotic progression have significant effects on the resulting daughter cells. Here we show...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Karki, Menuka, Keyhaninejad, Neda, Shuster, Charles B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474744/
https://ncbi.nlm.nih.gov/pubmed/28607478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15803
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