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Centrosomal Aki1 and cohesin function in separase-regulated centriole disengagement

Sister chromatid separation at anaphase is triggered by cleavage of the cohesin subunit Scc1, which is mediated by separase. Centriole disengagement also requires separase. This dual role of separase permits concurrent control of these events for accurate metaphase to anaphase transition. Although t...

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Bibliografske podrobnosti
Main Authors: Nakamura, Akito, Arai, Hiroyuki, Fujita, Naoya
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806580/
https://ncbi.nlm.nih.gov/pubmed/19948489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200906019
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