Metabolome and proteome changes with aging in Caenorhabditis elegans

To expand the understanding of aging in the model organism Caenorhabditis elegans, global quantification of metabolite and protein levels in young and aged nematodes was performed using mass spectrometry. With age there was a decreased abundance of proteins functioning in transcription termination,...

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Veröffentlicht in:Exp Gerontol
Hauptverfasser: Copes, Neil, Edwards, Clare, Chaput, Dale, Saifee, Mariam, Barjuca, Iosif, Nelson, Daniel, Paraggio, Alyssa, Saad, Patrick, Lipps, David, Stevens, Stanley M., Bradshaw, Patrick C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473633/
https://ncbi.nlm.nih.gov/pubmed/26390854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2015.09.013
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