Metabolome and proteome changes with aging in Caenorhabditis elegans

To expand the understanding of aging in the model organism Caenorhabditis elegans, global quantification of metabolite and protein levels in young and aged nematodes was performed using mass spectrometry. With age there was a decreased abundance of proteins functioning in transcription termination,...

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Publicat a:Exp Gerontol
Autors principals: Copes, Neil, Edwards, Clare, Chaput, Dale, Saifee, Mariam, Barjuca, Iosif, Nelson, Daniel, Paraggio, Alyssa, Saad, Patrick, Lipps, David, Stevens, Stanley M., Bradshaw, Patrick C.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473633/
https://ncbi.nlm.nih.gov/pubmed/26390854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2015.09.013
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