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D-beta-hydroxybutyrate extends lifespan in C. elegans

The ketone body beta-hydroxybutyrate (βHB) is a histone deacetylase (HDAC) inhibitor and has been shown to be protective in many disease models, but its effects on aging are not well studied. Therefore we determined the effect of βHB supplementation on the lifespan of C. elegans nematodes. βHB suppl...

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Detalhes bibliográficos
Main Authors: Edwards, Clare, Canfield, John, Copes, Neil, Rehan, Muhammad, Lipps, David, Bradshaw, Patrick C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169858/
https://ncbi.nlm.nih.gov/pubmed/25127866
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