D-beta-hydroxybutyrate extends lifespan in C. elegans

The ketone body beta-hydroxybutyrate (βHB) is a histone deacetylase (HDAC) inhibitor and has been shown to be protective in many disease models, but its effects on aging are not well studied. Therefore we determined the effect of βHB supplementation on the lifespan of C. elegans nematodes. βHB suppl...

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Bibliografske podrobnosti
Main Authors: Edwards, Clare, Canfield, John, Copes, Neil, Rehan, Muhammad, Lipps, David, Bradshaw, Patrick C.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169858/
https://ncbi.nlm.nih.gov/pubmed/25127866
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