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D-beta-hydroxybutyrate extends lifespan in C. elegans

The ketone body beta-hydroxybutyrate (βHB) is a histone deacetylase (HDAC) inhibitor and has been shown to be protective in many disease models, but its effects on aging are not well studied. Therefore we determined the effect of βHB supplementation on the lifespan of C. elegans nematodes. βHB suppl...

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Hlavní autoři: Edwards, Clare, Canfield, John, Copes, Neil, Rehan, Muhammad, Lipps, David, Bradshaw, Patrick C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169858/
https://ncbi.nlm.nih.gov/pubmed/25127866
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