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D-beta-hydroxybutyrate extends lifespan in C. elegans
The ketone body beta-hydroxybutyrate (βHB) is a histone deacetylase (HDAC) inhibitor and has been shown to be protective in many disease models, but its effects on aging are not well studied. Therefore we determined the effect of βHB supplementation on the lifespan of C. elegans nematodes. βHB suppl...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Impact Journals LLC
2014
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169858/ https://ncbi.nlm.nih.gov/pubmed/25127866 |
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