Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans

Single-gene mutations that disrupt mitochondrial respiratory chain function in C. elegans change patterns of protein expression and metabolites. Our goal was to develop useful molecular fingerprints employing adaptable techniques to recognize mitochondrial defects in the electron transport chain. We...

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Dettagli Bibliografici
Pubblicato in:Mitochondrion
Autori principali: Morgan, PG, Higdon, R, Kolker, N, Bauman, AT, Ilkayeva, O, Newgard, CB, Kolker, E, Steele, LM, Sedensky, MM
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305019/
https://ncbi.nlm.nih.gov/pubmed/25530493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2014.12.004
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