Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans

Single-gene mutations that disrupt mitochondrial respiratory chain function in C. elegans change patterns of protein expression and metabolites. Our goal was to develop useful molecular fingerprints employing adaptable techniques to recognize mitochondrial defects in the electron transport chain. We...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mitochondrion
Main Authors: Morgan, PG, Higdon, R, Kolker, N, Bauman, AT, Ilkayeva, O, Newgard, CB, Kolker, E, Steele, LM, Sedensky, MM
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305019/
https://ncbi.nlm.nih.gov/pubmed/25530493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2014.12.004
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