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Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex II
Succinate-driven reverse electron transport (RET) through complex I is hypothesized to be a major source of reactive oxygen species (ROS) that induces permeability transition pore (PTP) opening and damages the heart during ischemia/reperfusion. Because RET can only generate ROS when mitochondria are...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5473242/ https://ncbi.nlm.nih.gov/pubmed/28450394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.768325 |
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