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Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex III

Recent evidence has implicated succinate-driven reverse electron transport (RET) through complex I as a major source of damaging reactive oxygen species (ROS) underlying reperfusion injury after prolonged cardiac ischemia. However, this explanation may be incomplete, because RET on reperfusion is se...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Korge, Paavo, Calmettes, Guillaume, John, Scott A., Weiss, James N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473241/
https://ncbi.nlm.nih.gov/pubmed/28450391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.768317
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