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Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes
Functional consequences for most inflammatory disease-associated loci are incompletely defined, including in the LACC1 (C13orf31) region. Here we show that human peripheral and intestinal myeloid-derived cells express laccase domain-containing 1 (LACC1); LACC1 is expressed in both the cytoplasm and...
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| Publicado en: | Nat Commun |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5472760/ https://ncbi.nlm.nih.gov/pubmed/28593945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15614 |
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