Cohesin Mutations in Myeloid Malignancies

Acute Myeloid Leukemia (AML) is a hematologic malignancy with a poor prognosis. Recent genome-wide sequencing studies have identified frequent mutations in genes encoding members of the cohesin complex. Mutations in cohesin contribute to myeloid malignancies by conferring enhanced self-renewal of he...

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Publicado en:Trends Cancer
Autores principales: Fisher, Joseph B., McNulty, Maureen, Burke, Michael J., Crispino, John D., Rao, Sridhar
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472227/
https://ncbi.nlm.nih.gov/pubmed/28626802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2017.02.006
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