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Novel selective β(1)-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease
β-Blockers reduce mortality and improve symptoms in people with heart disease; however, current clinically available β-blockers have poor selectivity for the cardiac β(1)-adrenoceptor (AR) over the lung β(2)-AR. Unwanted β(2)-blockade risks causing life-threatening bronchospasm and reduced efficacy...
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Udgivet i: | FASEB J |
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Main Authors: | , , , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Federation of American Societies for Experimental Biology
2017
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5471521/ https://ncbi.nlm.nih.gov/pubmed/28400472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601305R |
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