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Synthesis and in Vitro and in Vivo Characterization of Highly β(1)-Selective β-Adrenoceptor Partial Agonists

[Image: see text] β-Adrenoceptor antagonists boast a 50-year use for symptomatic control in numerous cardiovascular diseases. One might expect highly selective antagonists are available for the human β-adrenoceptor subtype involved in these diseases, yet few truly β(1)-selective molecules exist. To...

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Main Authors: Mistry, Shailesh N., Baker, Jillian G, Fischer, Peter M, Hill, Stephen J, Gardiner, Sheila M, Kellam, Barrie
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2013
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694353/
https://ncbi.nlm.nih.gov/pubmed/23614528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400348g
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