Microbiota metabolite short chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43

Intestinal IgA, which is regulated by gut microbiota, plays a crucial role in maintenance of intestinal homeostasis and in protecting the intestines from inflammation. However, the means by which microbiota promotes intestinal IgA responses remain unclear. Emerging evidence suggests that the host ca...

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Dettagli Bibliografici
Pubblicato in:Mucosal Immunol
Autori principali: Wu, Wei, Sun, Mingming, Chen, Feidi, Cao, Anthony T, Liu, Han, Zhao, Ye, Huang, Xiangsheng, Xiao, Yi, Yao, Suxia, Zhao, Qihong, Liu, Zhanju, Cong, Yingzi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471141/
https://ncbi.nlm.nih.gov/pubmed/27966553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.114
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