Microbiota Metabolite Butyrate Differentially Regulates Th1 and Th17 Cells’ Differentiation and Function in Induction of Colitis

BACKGROUND: How the gut microbiota regulates intestinal homeostasis is not completely clear. Gut microbiota metabolite short-chain fatty acids (SCFAs) have been reported to regulate T-cell differentiation. However, the mechanisms underlying SCFA regulation of T-cell differentiation and function rema...

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Veröffentlicht in:Inflamm Bowel Dis
Hauptverfasser: Chen, Liang, Sun, Mingming, Wu, Wei, Yang, Wenjing, Huang, Xiangsheng, Xiao, Yi, Ma, Chunyan, Xu, Leiqi, Yao, Suxia, Liu, Zhanju, Cong, Yingzi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701512/
https://ncbi.nlm.nih.gov/pubmed/30918945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izz046
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