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A potential anti-tumor effect of leukotriene C(4) through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells
Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Cyclooxygenase-2, which plays a key role in the biosynthesis of prostaglandin E(2) (PGE(2)), is often up-regulated in CRC and in other types of cancer. PGE(2) induces angiogenesis and tumor cell survival, prolif...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5471032/ https://ncbi.nlm.nih.gov/pubmed/28402256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16591 |
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