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Tumour suppressor 15-hydroxyprostaglandin dehydrogenase induces differentiation in colon cancer via GLI1 inhibition

Inflammation is an established risk factor for colorectal cancer. We and others have shown that colorectal cancer patients with elevated cysteinyl leukotriene receptor 2 (CysLT(2)R) and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) levels exhibit good prognoses. However, both CysLT(2)R and 15-PGDH...

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發表在:Oncogenesis
Main Authors: Satapathy, Shakti Ranjan, Topi, Geriolda, Osman, Janina, Hellman, Karin, Ek, Fredrik, Olsson, Roger, Sime, Wondossen, Mehdawi, Lubna M., Sjölander, Anita
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438320/
https://ncbi.nlm.nih.gov/pubmed/32814764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00256-0
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