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miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer
Elevated prostaglandin E(2) (PGE(2)) levels are observed in colorectal cancer (CRC) patients, and this increase is associated with poor prognosis. Increased synthesis of PGE(2) in CRC has been shown to occur through COX-2-dependent mechanisms; however, loss of the PGE(2)-catabolizing enzyme, 15-hydr...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443653/ https://ncbi.nlm.nih.gov/pubmed/30931980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41862-2 |
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