Identification of a novel functional JAK1 S646P mutation in acute lymphoblastic leukemia

The survival rate of childhood acute lymphoblastic leukemia (ALL) is approaching 90%, while the prognosis of adults remains poor due to the limited therapeutic approaches. In order to identify new targets for ALL, we performed whole-exome sequencing on four adults with B-ALL and discovered a somatic...

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Foilsithe in:Oncotarget
Main Authors: Li, Qian, Li, Botao, Hu, Liangding, Ning, Hongmei, Jiang, Min, Wang, Danhong, Liu, Tingting, Zhang, Bin, Chen, Hu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2017
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471003/
https://ncbi.nlm.nih.gov/pubmed/28410228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16670
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