JAK mutations in high-risk childhood acute lymphoblastic leukemia

Pediatric acute lymphoblastic leukemia (ALL) is a heterogeneous disease consisting of distinct clinical and biological subtypes that are characterized by specific chromosomal abnormalities or gene mutations. Mutation of genes encoding tyrosine kinases is uncommon in ALL, with the exception of Philad...

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Autors principals: Mullighan, Charles G., Zhang, Jinghui, Harvey, Richard C., Collins-Underwood, J. Racquel, Schulman, Brenda A., Phillips, Letha A., Tasian, Sarah K., Loh, Mignon L., Su, Xiaoping, Liu, Wei, Devidas, Meenakshi, Atlas, Susan R., Chen, I-Ming, Clifford, Robert J., Gerhard, Daniela S., Carroll, William L., Reaman, Gregory H., Smith, Malcolm, Downing, James R., Hunger, Stephen P., Willman, Cheryl L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695045/
https://ncbi.nlm.nih.gov/pubmed/19470474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811761106
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