JAK mutations in high-risk childhood acute lymphoblastic leukemia

Pediatric acute lymphoblastic leukemia (ALL) is a heterogeneous disease consisting of distinct clinical and biological subtypes that are characterized by specific chromosomal abnormalities or gene mutations. Mutation of genes encoding tyrosine kinases is uncommon in ALL, with the exception of Philad...

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Bibliographic Details
Main Authors: Mullighan, Charles G., Zhang, Jinghui, Harvey, Richard C., Collins-Underwood, J. Racquel, Schulman, Brenda A., Phillips, Letha A., Tasian, Sarah K., Loh, Mignon L., Su, Xiaoping, Liu, Wei, Devidas, Meenakshi, Atlas, Susan R., Chen, I-Ming, Clifford, Robert J., Gerhard, Daniela S., Carroll, William L., Reaman, Gregory H., Smith, Malcolm, Downing, James R., Hunger, Stephen P., Willman, Cheryl L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695045/
https://ncbi.nlm.nih.gov/pubmed/19470474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811761106
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