JAK mutations in high-risk childhood acute lymphoblastic leukemia

Pediatric acute lymphoblastic leukemia (ALL) is a heterogeneous disease consisting of distinct clinical and biological subtypes that are characterized by specific chromosomal abnormalities or gene mutations. Mutation of genes encoding tyrosine kinases is uncommon in ALL, with the exception of Philad...

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Detalles Bibliográficos
Autores principales: Mullighan, Charles G., Zhang, Jinghui, Harvey, Richard C., Collins-Underwood, J. Racquel, Schulman, Brenda A., Phillips, Letha A., Tasian, Sarah K., Loh, Mignon L., Su, Xiaoping, Liu, Wei, Devidas, Meenakshi, Atlas, Susan R., Chen, I-Ming, Clifford, Robert J., Gerhard, Daniela S., Carroll, William L., Reaman, Gregory H., Smith, Malcolm, Downing, James R., Hunger, Stephen P., Willman, Cheryl L.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695045/
https://ncbi.nlm.nih.gov/pubmed/19470474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811761106
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