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Identification of a novel functional JAK1 S646P mutation in acute lymphoblastic leukemia
The survival rate of childhood acute lymphoblastic leukemia (ALL) is approaching 90%, while the prognosis of adults remains poor due to the limited therapeutic approaches. In order to identify new targets for ALL, we performed whole-exome sequencing on four adults with B-ALL and discovered a somatic...
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| Veröffentlicht in: | Oncotarget |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5471003/ https://ncbi.nlm.nih.gov/pubmed/28410228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16670 |
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