DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism

Osteoarthritis (OA) is the most common form of arthritis worldwide. It is a complex disease affecting the whole joint but is generally characterized by progressive degradation of articular cartilage. Recent genome-wide association screens have implicated distinct DNA methylation signatures in OA pat...

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Vydáno v:JCI Insight
Hlavní autoři: Shen, Jie, Wang, Cuicui, Li, Daofeng, Xu, Taotao, Myers, Jason, Ashton, John M., Wang, Ting, Zuscik, Michael J., McAlinden, Audrey, O’Keefe, Regis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470890/
https://ncbi.nlm.nih.gov/pubmed/28614801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93612
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