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Inhibition of 4-aminobutyrate aminotransferase protects against injury-induced osteoarthritis in mice
Recently we demonstrated that ablation of the DNA methyltransferase enzyme, Dnmt3b, resulted in catabolism and progression of osteoarthritis (OA) in murine articular cartilage through a mechanism involving increased mitochondrial respiration. In this study, we identify 4-aminobutyrate aminotransfera...
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| I publikationen: | JCI Insight |
|---|---|
| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Clinical Investigation
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6795381/ https://ncbi.nlm.nih.gov/pubmed/31534049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128568 |
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