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Identification of an Adenosine Receptor Domain Specifically Involved in Binding of 5′-Substituted Adenosine Agonists

The bovine A(1) adenosine receptor (A(1)AR) and rat A(3) adenosine receptor (A(3)AR) display distinct agonist and antagonist binding properties. To identify regions involved in ligand recognition, A(1)AR/A(3)AR chimeric receptors were created, expressed in COS-7 cells, and analyzed by radioligand bi...

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Publicat a:J Biol Chem
Autors principals: Olah, Mark E., Jacobson, Kenneth A., Stiles, Gary L.
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470540/
https://ncbi.nlm.nih.gov/pubmed/8027060
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